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Test ID HGNA Mercury, Nails

Reporting Name

Mercury, Nails

Useful For

Detecting mercury exposure

Specimen Type

Nail


Specimen Required


Supplies: Hair and Nails Collection Kit (T565)

Specimen Volume: 0.2 g

Collection Instructions:

1. Prepare and transport specimen per the instructions in the kit or see Collecting Hair and Nails for Metals Testing in Special Instructions.

2. Clippings should be taken from all 10 fingernails or toenails.

Additional Information: If known, indicate source of nails (fingernails or toenails).


Specimen Minimum Volume

0.05 g

Specimen Stability Information

Specimen Type Temperature Time
Nail Ambient (preferred)
  Frozen 
  Refrigerated 

Reference Values

0-15 years: not established

≥16 years: 0.0-0.9 mcg/g of nails

Day(s) and Time(s) Performed

Tuesday; 3 p.m.

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

83825

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HGNA Mercury, Nails 8204-0

 

Result ID Test Result Name Result LOINC Value
2509 Mercury, Nails 8204-0
HGNSC Specimen Source 31208-2

Clinical Information

Once absorbed and circulating, mercury becomes bound to numerous proteins, including keratin. The concentration of mercury in nails correlates with the severity of clinical symptoms. If the nails can be segregated by length, such an exercise can be useful in identifying the time of exposure.

Interpretation

Normally, nails contain less than 1 mcg/g of mercury; any amount more than this indicates that exposure to more than normal amounts of mercury has occurred.

Clinical Reference

1. Marques RC, Dorea JG, Bastos WR, Malm O: Changes in children hair-Hg concentrations during the first 5 years: maternal, environmental and iatrogenic modifying factors. Reg Toxicol Pharmacol 2007;49:17-24

2. Canuel R, de Grosbois SB, Atikesse L, et al: New evidence on variations of human body burden of methylmercury from fish consumption. Environ Health Perspect 2006;114:302-306

Analytic Time

2 days

Method Name

Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)