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Test ID LPNF1 Lipid Panel, Non-Fasting, Serum


Specimen Required


Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 1 mL

Collection Instructions:

1. Serum gel tube must be centrifuged within 2 hours of draw time.

2. Red-top tube must be centrifuged and aliquoted within 2 hours of draw time.


Useful For

Evaluation of cardiovascular risk

Profile Information

Test ID Reporting Name Available Separately Always Performed
CHOL Cholesterol, Total, S Yes Yes
TRIGN Triglycerides, Non-Fasting, S Yes Yes
HDCH Cholesterol, HDL, S Yes Yes
CLDLN LDL Cholesterol, Non-Fasting No Yes
NHDCH Non HDL Cholesterol No Yes

Method Name

CHOL, TRIGN, HDCH: Enzymatic Colorimetric

CLDLN: Friedewald Equation

NHDCH: Total Cholesterol-HDL Cholesterol

Reporting Name

Lipid Panel, Non-Fasting

Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Frozen  30 days

Clinical Information

Cardiovascular disease is the number one cause of death in the United States with an estimated 1.5 million heart attacks and 0.5 million strokes occurring annually, many in individuals who have no prior symptoms. Prevention of ischemic cardiovascular events is key. Risk factors, including age, smoking status, hypertension, diabetes, cholesterol, and HDL cholesterol, are used by physicians to identify individuals likely to have an ischemic event.

Reference Values

The National Lipid Association and the National Cholesterol Education Program (NCEP) have set the following guidelines for lipids (total cholesterol, triglycerides, HDL cholesterol, LDL cholesterol, and non HDL cholesterol) in adults ages 18 and up:

 

TOTAL CHOLESTEROL

Desirable: <200 mg/dL

Borderline high: 200-239 mg/dL

High: ≥240 mg/dL

 

TRIGLYCERIDES

Males

<200 mg/dL

Females

<175 mg/dL

 

HDL CHOLESTEROL

Males

≥40 mg/dL

Females

≥50 mg/dL

 

LDL CHOLESTEROL

Desirable: <100 mg/dL

Above desirable: 100-129 mg/dL

Borderline high: 130-159 mg/dL

High: 160-189 mg/dL

Very high: ≥190 mg/dL

 

NON HDL CHOLESTEROL

Desirable: <130 mg/dL

Above desirable: 130-159 mg/dL

Borderline high: 160-189 mg/dL

High: 190-219

Very high: ≥220 mg/dL

 

The Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents has set the following guidelines for lipids (total cholesterol, triglycerides, HDL cholesterol, LDL cholesterol, and non-HDL cholesterol) in children ages 2-17 years of age:

 

TOTAL CHOLESTEROL

Acceptable: <170 mg/dL

Borderline high: 170-199 mg/dL

High: ≥200 mg/dL

 

TRIGLYCERIDES

2-9 years:

Acceptable: <75 mg/dL

Borderline high: 75-99 mg/dL

High: ≥100mg/dL

10-17 years:

Acceptable: <90 mg/dL

Borderline high: 90-129 mg/dL

High: ≥130 mg/dL

 

HDL CHOLESTEROL

Low HDL: <40 mg/dL

Borderline low: 40-45 mg/dL

Acceptable: >45 mg/dL

 

LDL CHOLESTEROL

Acceptable: <110 mg/dL

Borderline high: 110-129 mg/dL

High: ≥130 mg/dL

 

NON HDL CHOLESTEROL

Acceptable: <120 mg/dL

Borderline high: 120-144 mg/dL

High: ≥145 mg/dL

Interpretation

Mayo Clinic has adopted the National Lipid Association classifications, which are included as reference values on Mayo Clinic and Mayo Clinical Laboratories reports (see Reference Values). Lipids are most commonly measured to assess cardiovascular risk. Maintaining desirable concentrations of lipids lowers the risk of heart attacks or strokes. Establishing appropriate treatment strategies and lipid goals require the results for each component of a lipid profile to be considered in context with other risk factors including, age, sex, smoking status, family and personal history of heart disease. Nonfasting lipids are endorsed by the 2013 American College of Cardiology/American Heart Association (ACC/AHA) guidelines, in which a follow-up fasting sample is recommended if triglycerides exceed normal levels.

Clinical Reference

1. Jacobson TA, Ito MK, Maki KC, et al: National Lipid Association recommendations for patient-centered management of dyslipidemia: part 1-executive summary. J Clin Lipidol 2014 Sep-Oct;8(5):473-488

2. Goff DC, Lloyd-Jones DM, Gennett G, et al: 2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk. Circulation 2014;129:S49-S73

3. Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents; National Heart, Lung, and Blood Institute: Expert panel on integrated guidelines for cardiovascular health and risk reduction in children and adolescents. Pediatrics 2011;128;S213-S256

Day(s) and Time(s) Performed

Monday through Sunday; Continuously

Analytic Time

Same day/1 day

Test Classification

This test has been cleared, approved or is exempt by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

80061-Lipid panel (if all 3 performed)

82465-Cholesterol, total (if all 3 are not performed)

84478-Triglycerides (if all 3 are not performed)

83718-Cholesterol, HDL (if all 3 are not performed)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
LPNF1 Lipid Panel, Non-Fasting 24331-1

 

Result ID Test Result Name Result LOINC Value
CHOL Cholesterol, Total, S 2093-3
HDCH Cholesterol, HDL, S 2085-9
NHDCH Non HDL Cholesterol 43396-1
TRIGN Triglycerides, Non-Fasting, S 2571-8
CLDLN LDL Cholesterol, Non-Fasting 13457-7