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Test ID MCA Myocardial Antibodies, Serum

Reporting Name

Myocardial Abs, S

Useful For

Evaluating patients suspected of having post cardiotomy or post myocardial infarction syndromes


Evaluating patients suspected of having inflammatory cardiomyopathy

Specimen Type


Specimen Required


Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 0.5 mL

Specimen Minimum Volume

0.2 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Frozen  14 days

Reference Values


If positive, results are titered.

Reference values apply to all ages.

Day(s) and Time(s) Performed

Monday through Sunday; 11 a.m.

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information


86256-Titer (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
MCA Myocardial Abs, S 5260-5


Result ID Test Result Name Result LOINC Value
9746 Myocardial Abs, S 5260-5

Clinical Information

Myocardial antibodies occur in the sera of patients who have acute rheumatic fever and carditis, or who have sustained mechanical (surgical or traumatic) or ischemic damage to myocardial tissue in the postcardiotomy and post myocardial infarction syndromes.


In the "myocardial injury" syndromes, circulating myocardial antibodies become detectable 2 to 3 weeks after the injury in 30% (infarction) to 70% (postsurgical) of cases and remain detectable for 3 to 8 weeks.


Myocardial antibodies have been detected in some patients with idiopathic cardiomyopathy.


The pathogenic significance of myocardial antibodies is not known.


Elevated in 30% of myocardial injury patients by the 2nd or 3rd week

Clinical Reference

Twomey SL, Bernett GE: Immunofluorescence method for detecting anti-myocardial antibodies, and its use in diagnosing heart disease. Clin Chem 1975;21:1903-1906

Analytic Time

1 day

Method Name

Indirect Immunofluorescence