Sign in →

Test ID BMAMA Basic Metabolic Panel, Serum


Necessary Information


Patient's age and sex are required.

Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions:

1. Serum gel tubes should be centrifuged within 2 hours of collection.

2. Red-top tubes should be centrifuged and the serum aliquoted into a plastic vial within 2 hours of collection.


Useful For

Routine health monitoring or patient monitoring while hospitalized for information regarding metabolism, including the current kidney status, electrolyte, and acid/base balance, and blood glucose

Profile Information

Test ID Reporting Name Available Separately Always Performed
KS Potassium, S Yes Yes
NAS Sodium, S Yes Yes
CL Chloride, S Yes Yes
HCO3 Bicarbonate, S Yes Yes
AGAP Anion Gap No Yes
BUN Bld Urea Nitrog (BUN), S Yes Yes
CRTS1 Creatinine with eGFR, S Yes Yes
CA Calcium, Total, S Yes Yes
GLURA Glucose, Random, S Yes Yes

Method Name

KS, NAS, CL: Potentiometric, Indirect Ion-Selective Electrode

HCO3: Photometric/Enzymatic

AGAP: Calculation

BUN: Photometric, Urease

CRTS1: Enzymatic Colorimetric Assay

CA: Photometric

GLURA: Enzymatic Photometric Assay

Reporting Name

Basic Metabolic Panel, S

Specimen Type

Serum

Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated 24 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia OK

Clinical Information

The basic metabolic panel measures 8 analytes and calculates an anion gap. It is used to assess kidney status, electrolyte, and acid/base balance, and blood glucose.

Reference Values

SODIUM

<1 year: Not established

≥1 year: 135-145 mmol/L

 

POTASSIUM

<1 year: Not established

≥1 year: 3.6-5.2 mmol/L

 

CHLORIDE

<1 year: Not established

1-17 years: 102-112 mmol/L

≥18 years: 98-107 mmol/L

 

BICARBONATE

Males:

<1 year: Not established

1-2 years: 17-25 mmol/L

3 years: 18-26 mmol/L

4-5 years: 19-27 mmol/L

6-7 years: 20-28 mmol/L

8-17 years: 21-29 mmol/L

≥18 years: 22-29 mmol/L

 

Females:

<1 year: Not established

1-3 years: 18-25 mmol/L

4-5 years: 19-26 mmol/L

6-7 years: 20-27 mmol/L

8-9 years: 21-28 mmol/L

≥10 years: 22-29 mmol/L

 

ANION GAP

<7 years: Not established

≥7 years: 7-15

 

BLOOD UREA NITROGEN

Males:

<12 months: Not established

1-17 years: 7-20 mg/dL

≥18 years: 8-24 mg/dL

 

Females:

<12 months: Not established

1-17 years: 7-20 mg/dL

≥18 years: 6-21 mg/dL

 

CREATININE

Males:

0-11 months: 0.17-0.42 mg/dL

1-5 years: 0.19-0.49 mg/dL

6-10 years: 0.26-0.61 mg/dL

11-14 years: 0.35-0.86 mg/dL

≥15 years: 0.74-1.35 mg/dL

 

Females:

0-11 months: 0.17-0.42 mg/dL

1-5 years: 0.19-0.49 mg/dL

6-10 years: 0.26-0.61 mg/dL

11-15 years: 0.35-0.86 mg/dL

≥16 years: 0.59-1.04 mg/dL

 

ESTIMATED GLOMERULAR FILTRATION RATE (eGFR)

≥ 18 years old: ≥60 mL/min/BSA (body surface area)

Estimated GFR calculated using the 2021 CKD-EPI creatinine equation

Note: eGFR results will not be calculated for patients younger than 18 years old.

 

CALCIUM

<1 year: 8.7-11.0 mg/dL

1-17 years: 9.3-10.6 mg/dL

18-59 years: 8.6-10.0 mg/dL

60-90 years: 8.8-10.2 mg/dL

>90 years: 8.2-9.6 mg/dL

 

GLUCOSE

0-11 months: Not established

≥1 year: 70-140 mg/dL

Interpretation

Basic metabolic panel results are usually evaluated in conjunction with each other for patterns of results. A single abnormal test result could be indicative of something different than if more than 1 of the test results are abnormal. Many conditions will cause abnormal results including kidney failure, breathing problems, and diabetes-related complications.

Cautions

No significant cautionary statements

Clinical Reference

1. Oh MS: Evaluation of renal function, water, electrolytes, and acid-base balance. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 22nd ed. Elsevier Saunders; 2011:chap 14

2. Basic Metabolic Panel (BMP). Testing.com; Updated November 9, 2021. Accessed July 13, 2022. Available at www.testing.com/tests/basic-metabolic-panel-bmp/

Method Description

Sodium, Potassium, Chloride:

The ion selective electron (ISE) module indirectly measures the electromotive force (EMF) difference between an ISE and a reference electrode. The EMF of the ISE is dependent on the ion concentration of the sample. The EMF of the reference electrode is constant. An electronic calculation circuit converts EMF of the sample to the ion concentration of the sample.(Package insert: ISE Indirect Na, K, CL: for Gen 2. Roche Diagnostics; 12/2020)

 

Bicarbonate:

This is a photometric rate reaction. Bicarbonate (HCO3[-]) reacts with phosphoenolpyruvate in the presence of phosphoenolpyruvate carboxylase to produce oxaloacetate and phosphate. The oxaloacetate produced is coupled with reduced nicotinamide adenine dinucleotide (NADH) in the presence of malate dehydrogenase to produce malate and NAD(+). The consumption of NADH causes a decrease in absorbance and is monitored in the ultraviolet range of 320 to 400 nm. The rate of change is directly proportional to the concentration of bicarbonate.(Package insert: Bicarbonate reagent. Roche Diagnostics; 04/2019)

 

Anion Gap:

This is a calculated result. The following equation is used to calculate the anion gap (A gap):

A gap =Na - (Cl + HCO3[-])

 

Blood Urea Nitrogen:

This is a kinetic UV assay where urease cleaves urea to form ammonia and carbon dioxide. The ammonia formed then reacts with alpha-ketoglutarate and NADH in the presence of urease/glutamate dehydrogenase to yield glutamate and NAD(+). The decrease in absorbance, due to the consumption of NADH, is measured kinetically and is proportional to the amount of urea in the sample.(Package insert: Urea/BUN reagent. Roche Diagnostics; 12/2019)

 

Creatinine:

This enzymatic method is based on the conversion of creatinine with the aid of creatininase, creatinase, and sarcosine oxidase to glycine, formaldehyde, and hydrogen peroxide. Catalyzed by peroxidase the liberated hydrogen peroxide reacts with 4-aminophenazone and HTIB (hydroxy[tosyloxy]iodobenzene) to form a quinone imine chromogen. The color intensity of the quinone imine chromogen formed is directly proportional to the creatinine concentration in the reaction mixture.(Package insert: Creatinine Plus ver.2. Roche Diagnostics; 02/2019)

 

Calcium:

Calcium ions react with NM-BAPTA (5-nitro-5'-methyl-1,2-bis[o-aminophenoxy]ethane-N,N,N',N'-tetraacetic acid) under alkaline conditions to form a complex. This complex reacts in the second step with EDTA. The change in absorbance is directly proportional to the calcium concentration and is measured photometrically.(Package insert: Calcium Gen.2 reagent, Roche Diagnostics; 07/2019)

 

Glucose:

Glucose in the sample, in the presence of hexokinase, is converted to glucose-6-phosphate (G6P). In the presence of nicotinamide adenine dinucleotide phosphate (NADP[+]), glucose-6-phosphate dehydrogenase oxides G6P to gluconate-6-phosphate and NADPH. The rate of NADPH formation is directly proportional to glucose concentration in the sample and is measured photometrically.(Package insert: Glucose Gen.3 Reagent. Roche Diagnostics; 11/2021)

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 to 2 days

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

84132

84295

82435

82374

84520

82565

82310

82947

NY State Approved

Yes

Forms

If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.