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HelpTest ID CDB Cadmium, Blood
Reporting Name
Cadmium, BUseful For
Detecting exposure to cadmium, a toxic heavy metal
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
Whole bloodSpecimen Required
Container/Tube: Royal blue-top (EDTA) Vacutainer plastic trace element blood collection tube (T183)
Specimen Volume: Full tube
Collection Instructions:
1. See Trace Metals Analysis Specimen Collection and Transport in Special Instructions for complete instructions.
2. Send specimen in original tube.
Additional Information:
1. High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
2. If ordering the trace element blood collection tube from BD, order catalog #368381.
Specimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Whole blood | Refrigerated (preferred) | 28 days |
| Ambient | 28 days | |
| Frozen | 28 days |
Special Instructions
Reference Values
0.0-4.9 ng/mL
Reference values apply to all ages.
Day(s) and Time(s) Performed
Monday through Saturday; 2 p.m.
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
82300
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CDB | Cadmium, B | 5609-3 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 8682 | Cadmium, B | 5609-3 |
Clinical Information
The toxicity of cadmium resembles the other heavy metals (arsenic, mercury, and lead) in that it attacks the kidney; renal dysfunction with proteinuria with slow onset (over a period of years) is the typical presentation.
Breathing the fumes of cadmium vapors leads to nasal epithelial deterioration and pulmonary congestion resembling chronic emphysema.
The most common source of chronic exposure comes from spray painting of organic-based paints without use of a protective breathing apparatus; auto repair mechanics represent a susceptible group for cadmium toxicity. In addition, another common source of cadmium exposure is tobacco smoke.
Interpretation
Normal blood cadmium is <5.0 ng/mL, with most results in the range of 0.5 to 2.0 ng/mL.
Acute toxicity will be observed when the blood level exceeds 50 ng/mL.
Cautions
High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen cannot be collected for 96 hours.
Clinical Reference
Moreau T, Lellouch J, Juguet B, et al: Blood cadmium levels in a general population with special reference to smoking. Arch Environ Health 1983;38:163-167
Analytic Time
1 dayReject Due To
|
Hemolysis |
Mild OK; Gross OK |
|
Lipemia |
Mild OK; Gross OK |
|
Icterus |
Mild OK; Gross OK |
|
Other |
Green-top (heparin) tube |
NY State Approved
YesMethod Name
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)