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HelpTest ID CDB Cadmium, Blood
Reporting Name
Cadmium, BUseful For
Detecting exposure to cadmium, a toxic heavy metal
Specimen Type
Whole bloodSpecimen Required
Patient Preparation: High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
Supplies: Metal Free B-D Tube (EDTA), 6 mL (T183)
Container/Tube: Royal blue-top (EDTA) plastic trace element blood collection tube
Specimen Volume: Full tube
Collection Instructions: Send specimen in original tube.
Additional Information: If ordering the trace element blood collection tube from BD, order catalog #368381.
Specimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Whole blood | Refrigerated (preferred) | 28 days | |
| Ambient | 28 days | ||
| Frozen | 28 days |
Reference Values
<5.0 ng/mL
Reference values apply to all ages.
Day(s) and Time(s) Performed
Monday through Saturday; 2 p.m.
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
82300
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CDB | Cadmium, B | 5609-3 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 8682 | Cadmium, B | 5609-3 |
Clinical Information
The toxicity of cadmium resembles the other heavy metals (arsenic, mercury, and lead) in that it attacks the kidney; renal dysfunction with proteinuria with slow onset (over a period of years) is the typical presentation.
Breathing the fumes of cadmium vapors leads to nasal epithelial deterioration and pulmonary congestion resembling chronic emphysema.
The most common source of chronic exposure comes from spray painting of organic-based paints without use of a protective breathing apparatus; auto repair mechanics represent a susceptible group for cadmium toxicity. In addition, another common source of cadmium exposure is tobacco smoke.
Interpretation
Normal blood cadmium is <5.0 ng/mL, with most results in the range of 0.5 to 2.0 ng/mL.
Acute toxicity will be observed when the blood level exceeds 50 ng/mL.
Clinical Reference
1. Moreau T, Lellouch J, Juguet B, et al: Blood cadmium levels in a general population with special reference to smoking. Arch Environ Health. 1983;38:163-167
2. Strathmann FG, Blum LM: Toxic Elements. In: Rafai N, Horwath AR., Wittwer CT, eds. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics 6th ed. Elsevier, 2018;chap 42
Analytic Time
1 dayMethod Name
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)