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Test ID DCTR Direct Antiglobulin Test (Polyspecific), Blood


Shipping Instructions


Specimen must arrive within 48 hours of draw.



Specimen Required


Container/Tube: Pink top (EDTA)

Specimen Volume: 6 mL


Useful For

Demonstrating in vivo coating of RBCs with IgG or the complement component C3d in the following settings:

-Autoimmune hemolytic anemia

-Hemolytic transfusion reactions

-Drug-induced hemolytic anemia

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
DATR Direct Antiglobulin Tst (Poly) No No
DC3TR Direct Antiglobulin Test (C3) No No
DIGTR Direct Antiglobulin Test (IgG) No No

Testing Algorithm

When the direct antigobulin tests is positive, the DCTR test will be interpreted as “Invalid – See addl testing” and the DATR test will be performed. When direct antiglobulin (DATR) is positive, then the DATR reflex tests, DAT complement 3 and DAT IgG, will be performed at an additional charge.

Method Name

Hemagglutination

Reporting Name

Direct Antiglobulin Test (Poly)

Specimen Type

Whole Blood EDTA

Specimen Minimum Volume

3 mL
Neonates: EDTA Micro tube 0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Whole Blood EDTA Ambient (preferred) 48 hours
  Refrigerated  48 hours

Clinical Information

IgG antibody or complement components secondary to the action of IgM antibody may be present on the patient's own RBCs or on transfused RBCs.

Reference Values

Negative

If positive, test DATR will be performed.

Interpretation

Negative: No IgG antibody or complement (C3d) detected on the surface of the red cell.

 

Positive: Test DATR will be ordered and performed.

Clinical Reference

AABB Technical Manual. 19th edition. Edited by MK Fung, AF Eder, SL Spitalnik, CM Westhoff. AABB, 2017

Day(s) and Time(s) Performed

Monday through Friday, Sunday; Continuously

Analytic Time

Same day/1 day

Test Classification

This test has been cleared, approved or is exempt by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86880

LOINC Code Information

Test ID Test Order Name Order LOINC Value
DCTR Direct Antiglobulin Test (Poly) 1007-4

 

Result ID Test Result Name Result LOINC Value
DCTR Direct Antiglobulin Test (Poly) 1007-4