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Test ID LIVPR Liver Profile, Serum


Shipping Instructions


Ship specimen in amber vial to protect from light.



Necessary Information


Patient's age and sex are required.



Specimen Required


Supplies: Amber Frosted Tube, 5 mL (T192)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Amber vial (T192)

Specimen Volume: 0.6 mL

Collection Instructions:

1. Serum gel tubes should be centrifuged within 2 hours of collection.

2. Red-top tubes should be centrifuged and aliquoted within 2 hours of collection.


Useful For

Screening for liver damage, especially if someone has a condition or is taking a drug that may affect the liver

Method Name

BILIT: Photometric, Diazonium Salt (DPD)

BILID: Photometric, Diazotized Sulfanilic Acid

AST: Photometric Rate, L-Aspartate with Pyridoxyl-5-Phosphate

ALT: Photometric Rate, L-Alanine with Pyridoxal-5-Phosphate

ALP: Photometric, p-Nitrophenol Phosphate

ALB: Photometric, Bromcresol Green

TP: Colorimetric, Biuret

Reporting Name

Hepatic Function Panel, S

Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated 7 days

Clinical Information

The hepatic function panel may be used to help diagnose liver disease if a person has signs and symptoms that indicate possible liver dysfunction. If a person has a known condition or liver disease, testing may be performed at intervals to monitor the health of the liver and to evaluate the effectiveness of any treatments. Abnormal tests on a liver panel may prompt a repeat analysis of one or more tests, or of the whole panel, to see if the elevations or decreases persist and may indicate the need for additional testing to determine the cause of the liver dysfunction.

Reference Values

TOTAL BILIRUBIN

0-6 days: Refer to http://bilitool.org/ for information on age-specific (postnatal hour of life) serum bilirubin values.

7-14 days: <15.0 mg/dL

15 days to 17 years: ≤1.0 mg/dL

>18 years: ≤1.2 mg/dL

 

DIRECT BILIRUBIN

≥12 months: 0.0-0.3 mg/dL

Reference values have not been established for patients who are under 12 months of age.

 

ASPARTATE AMINOTRANSFERASE

Males

0-11 months: not established

1-13 years: 8-60 U/L

≥14 years: 8-48 U/L

 

Females

0-11 months: not established

1-13 years: 8-50 U/L

≥14 years: 8-43 U/L

 

ALANINE AMINOTRANSFERAASE

Males

≥1 year: 7-55 U/L

Reference values have not been established for patients who are under 12 months of age.

 

Females

≥1 year: 7-45 U/L

Reference values have not been established for patients who are under 12 months of age.

 

ALKALINE PHOSPHATASE

Males

4 years: 149-369 U/L

5 years: 179-416 U/L

6 years: 179-417 U/L

7 years: 172-405 U/L

8 years: 169-401 U/L

9 years: 175-411 U/L

10 years: 191-435 U/L

11 years: 185-507 U/L

12 years: 185-562 U/L

13 years: 182-587 U/L

14 years: 166-571 U/L

15 years: 138-511 U/L

16 years: 102-417 U/L

17 years: 69-311 U/L

18 years: 52-222 U/L

≥19 years: 45-115 U/L

 

Females

4 years: 169-372 U/L

5 years: 162-355 U/L

6 years: 169-370 U/L

7 years: 183-402 U/L

8 years: 199-440 U/L

9 years: 212-468 U/L

10 years: 215-476 U/L

11 years: 178-526 U/L

12 years: 133-485 U/L

13 years: 120-449 U/L

14 years: 153-362 U/L

15 years: 75-274 U/L

16 years: 61-264 U/L

17-23 years: 52-144 U/L

24-45 years: 37-98 U/L

46-50 years: 39-100 U/L

51-55 years: 41-108 U/L

56-60 years: 46-118 U/L

61-65 years: 50-130 U/L

≥66 years: 55-142 U/L

Reference values have not been established for patients who are under 4 years of age.

 

ALBUMIN

≥12 months: 3.5-5.0 g/dL

Reference values have not been established for patients who are under 12 months of age.

 

TOTAL PROTEIN

≥1 year: 6.3-7.9 g/dL

Reference values have not been established for patients who are under 12 months of age.

Interpretation

Hepatic function panel results are not diagnostic of a specific condition; they indicate that there may be a problem with the liver. In a person who does not have symptoms or identifiable risk factors, abnormal liver test results may indicate a temporary liver injury or reflect something that is happening elsewhere in the body-such as in the skeletal muscles, pancreas, or heart. It may also indicate early liver disease and the need for further testing and periodic monitoring.

 

Results of liver panels are usually evaluated together. Several sets of results from tests performed over a few days or weeks are often assessed together to determine if a pattern is present. Each person will have a unique set of test results that will typically change over time. A healthcare practitioner evaluates the combination of liver test results to gain clues about the underlying condition. Often, further testing is necessary to determine what is causing the liver damage or disease.

Clinical Reference

AACC: Lab Tests Online. Access 04/17/2018. Available at https://labtestsonline.org/understanding/analytes/liver-panel

Day(s) and Time(s) Performed

Monday through Sunday; Continuously

Analytic Time

Same day/1 day

Test Classification

This test has been cleared, approved or is exempt by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

80076

82247

82248

84450

84460

84075

82040

84155

LOINC Code Information

Test ID Test Order Name Order LOINC Value
LIVPR Hepatic Function Panel, S 24325-3

 

Result ID Test Result Name Result LOINC Value
BILIT Bilirubin Total, S 1975-2
BILID Bilirubin, Direct 1968-7
AST Aspartate Aminotransferase (AST), S 30239-8
ALT Alanine Aminotransferase (ALT), S 1743-4
ALP Alkaline Phosphatase, S 6768-6
ALB Albumin, S 1751-7
TP Protein, Total, S 2885-2