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Test ID RFAMA Renal Function Panel, Serum


Necessary Information


Patient's age and sex are required.



Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.6 mL

Collection Instructions:

1. Serum gel tubes should be centrifuged within 2 hours of collection.

2. Red-top tubes should be centrifuged and the serum aliquoted into a plastic vial within 2 hours of collection.


Useful For

Aiding in diagnosis and management of conditions affecting kidney function

 

General health screening

 

Screening patients at risk of developing kidney disease

 

Management of patients with known kidney disease

Profile Information

Test ID Reporting Name Available Separately Always Performed
KS Potassium, S Yes Yes
NAS Sodium, S Yes Yes
CL Chloride, S Yes Yes
HCO3 Bicarbonate, S Yes Yes
AGAP Anion Gap No Yes
BUN Bld Urea Nitrog (BUN), S Yes Yes
CRTS1 Creatinine with eGFR, S Yes Yes
CA Calcium, Total, S Yes Yes
GLURA Glucose, Random, S Yes Yes
ALB Albumin, S Yes Yes
PHOS Phosphorus (Inorganic), S Yes Yes

Method Name

KS, NAS, CL: Potentiometric, Indirect Ion-Selective Electrode

HCO3: Photometric, Enzymatic

AGAP: Calculated result

BUN: Photometric, Urease

CRTS1: Enzymatic Colorimetric Assay

CA: Photometric

GLURA: Photometric/Hexokinase

ALB: Photometric, Bromcresol Green

PHOS: Photometric, Ammonium Molybdate

Reporting Name

Renal Function Panel, S

Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated 24 hours

Clinical Information

This panel could be ordered when a patient has risk factors for kidney dysfunction such as high blood pressure (hypertension), diabetes, cardiovascular disease, obesity, elevated cholesterol, or a family history of kidney disease. This panel may also be ordered when someone has signs and symptoms of kidney disease, though early kidney disease often does not cause any noticeable symptoms. It may be initially detected through routine blood or urine testing.

Reference Values

SODIUM

<1 year: Not established

≥1 year: 135-145 mmol/L

 

POTASSIUM

<1 year: Not established

≥1 year: 3.6-5.2 mmol/L

 

CHLORIDE

<1 year: Not established

1-17 years: 102-112 mmol/L

≥18 years: 98-107 mmol/L

 

BICARBONATE

Males

<1 year: Not established

1-2 years: 17-25 mmol/L

3 years: 18-26 mmol/L

4-5 years: 19-27 mmol/L

6-7 years: 20-28 mmol/L

8-17 years: 21-29 mmol/L

≥18 years: 22-29 mmol/L

 

Females

<1 year: Not established

1-3 years: 18-25 mmol/L

4-5 years: 19-26 mmol/L

6-7 years: 20-27 mmol/L

8-9 years: 21-28 mmol/L

≥10 years: 22-29 mmol/L

 

ANION GAP

<7 years: Not established

≥7 years: 7-15

 

BLOOD UREA NITROGEN (BUN)

Males

<12 months: Not established

1-17 years: 7-20 mg/dL

≥18 years: 8-24 mg/dL

 

Females

<12 months: Not established

1-17 years: 7-20 mg/dL

≥18 years: 6-21 mg/dL

 

CREATININE

Males

0-11 months: 0.17-0.42 mg/dL

1-5 years: 0.19-0.49 mg/dL

6-10 years: 0.26-0.61 mg/dL

11-14 years: 0.35-0.86 mg/dL

≥15 years: 0.74-1.35 mg/dL

 

Females

0-11 months: 0.17-0.42 mg/dL

1-5 years: 0.19-0.49 mg/dL

6-10 years: 0.26-0.61 mg/dL

11-15 years: 0.35-0.86 mg/dL

≥16 years: 0.59-1.04 mg/dL

 

ESTIMATED GLOMERULAR FILTRATION RATE (eGFR)

 

≥ 18 years old: ≥60 mL/min/BSA (body surface area)

Estimated GFR calculated using the 2021 CKD-EPI creatinine equation.

Note: eGFR results will not be calculated for patients younger than 18 years old.

 

CALCIUM

<1 year: 8.7-11.0 mg/dL

1-17 years: 9.3-10.6 mg/dL

18-59 years: 8.6-10.0 mg/dL

60-90 years: 8.8-10.2 mg/dL

>90 years: 8.2-9.6 mg/dL

 

GLUCOSE

0-11 months: Not established

≥1 year: 70-140 mg/dL

 

Total Protein

≥1 year: 6.3-7.9 g/dL

Reference values have not been established for patients who are younger than 12 months of age.

 

ALBUMIN

≥12 months: 3.5-5.0 g/dL

Reference values have not been established for patients who are younger than 12 months of age.

 

PHOSPHORUS

Males

1-4 years: 4.3-5.4 mg/dL

5-13 years: 3.7-5.4 mg/dL

14-15 years: 3.5-5.3 mg/dL

16-17 years: 3.1-4.7 mg/dL

≥18 years: 2.5-4.5 mg/dL

Reference values have not been established for patients that are younger than 12 months of age.

 

Females

1-7 years: 4.3-5.4 mg/dL

8-13 years: 4.0-5.2 mg/dL

14-15 years: 3.5-4.9 mg/dL

16-17 years: 3.1-4.7 mg/dL

≥18 years: 2.5-4.5 mg/dL

Reference values have not been established for patients that are younger than 12 months of age.

Interpretation

Panel results are not diagnostic but rather indicate that there may be a problem with the kidneys and that further testing is required to make a diagnosis and determine the cause. Results of the panel are usually considered together, rather than separately. Individual test results can be abnormal due to causes other than kidney disease but taken together with risks and signs and symptoms, they may give an indication of whether kidney disease is present.

Clinical Reference

1. Oh MS: Evaluation of renal function, water, electrolytes, and acid-base balance. In: McPherson RA, Pincus MR, eds.  Henry's Clinical Diagnosis and Management by Laboratory Methods. 22nd ed. Elsevier Saunders; 2011:chap 14

2. Renal Panel. Testing.com; Updated November 9, 2021. Accessed July 14, 2022. Available at www.testing.com/tests/renal-panel/

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 to 2 days

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

KS: 84132

NAS: 84295

CL: 82435

HCO3: 82374

BUN: 84520

CRTS1: 82565

CA: 82310

GLURA: 82947

ALB: 82040

PHOS: 84100

LOINC Code Information

Test ID Test Order Name Order LOINC Value
RFAMA Renal Function Panel, S 24362-6

 

Result ID Test Result Name Result LOINC Value
AGAP Anion Gap 33037-3
ALB Albumin, S 1751-7
BUN Bld Urea Nitrog (BUN), S 3094-0
CL Chloride, S 2075-0
GLURA Glucose, Random, S 2345-7
HCO3 Bicarbonate, S 1963-8
PHOS Phosphorus (Inorganic), S 2777-1
CA Calcium, Total, S 17861-6
NAS Sodium, S 2951-2
KS Potassium, S 2823-3
CRTSA Creatinine, S 2160-0
EGFR1 Estimated GFR (eGFR) 2160-0

Forms

If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.