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HelpTest ID RFAMA Renal Function Panel, Serum
Necessary Information
Patient's age and sex are required.
Specimen Required
Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Specimen Volume: 0.6 mL
Collection Instructions:
1. Serum gel tubes should be centrifuged within 2 hours of collection.
2. Red-top tubes should be centrifuged and aliquoted within 2 hours of collection.
Useful For
Aids in diagnosis and management of conditions affecting kidney function
General health screening
Screening patients at risk of developing kidney disease
Management of patients with known kidney disease
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| KS | Potassium, S | Yes | Yes |
| NAS | Sodium, S | Yes | Yes |
| CL | Chloride, S | Yes | Yes |
| HCO3 | Bicarbonate, S | Yes | Yes |
| AGAP | Anion Gap | No | Yes |
| BUN | Bld Urea Nitrog(BUN), S | Yes | Yes |
| CRTS1 | Creatinine with eGFR, S | Yes | Yes |
| CA | Calcium, Total, S | Yes | Yes |
| GLURA | Glucose, Random, S | Yes | Yes |
| ALB | Albumin, S | Yes | Yes |
| PHOS | Phosphorus (Inorganic), S | Yes | Yes |
Method Name
KS, NAS, CL: Potentiometric, Indirect Ion-Selective Electrode
HCO3: Photometric, Enzymatic
AGAP: Sodium-(Bicarbonate + Chloride)
BUN: Photometric, Urease
CRTS1: Enzymatic Colorimetric Assay
CA: Photometric, 5-nitro-5'-methyl-BAPTA
GLURA: Photometric/Hexokinase
ALB: Photometric, Bromcresol Green
PHOS: Photometric, Ammonium Molybdate
Reporting Name
Renal Function Panel, SSpecimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated | 24 hours |
Clinical Information
A renal function panel could be ordered when a patient has risk factors for kidney dysfunction such as high blood pressure (hypertension), diabetes, cardiovascular disease, obesity, elevated cholesterol, or a family history of kidney disease. A renal function panel may also be ordered when someone has signs and symptoms of kidney disease, though early kidney disease often does not cause any noticeable symptoms. It may be initially detected through routine blood or urine testing.
Reference Values
SODIUM
<1 year: not established
≥1 year: 135-145 mmol/L
POTASSIUM
<1 year: not established
≥1 year: 3.6-5.2 mmol/L
CHLORIDE
<1 year: not established
1-17 years: 102-112 mmol/L
≥18 years: 98-107 mmol/L
BICARBONATE
Males
<1 year: not established
1-2 years: 17-25 mmol/L
3 years: 18-26 mmol/L
4-5 years: 19-27 mmol/L
6-7 years: 20-28 mmol/L
8-17 years: 21-29 mmol/L
≥18 years: 22-29 mmol/L
Females
<1 year: not established
1-3 years: 18-25 mmol/L
4-5 years: 19-26 mmol/L
6-7 years: 20-27 mmol/L
8-9 years: 21-28 mmol/L
≥10 years: 22-29 mmol/L
ANION GAP
<7 years: not established
≥7 years: 7-15
BLOOD UREA NITROGEN (BUN)
Males
<12 months: not established
1-17 years: 7-20 mg/dL
≥18 years: 8-24 mg/dL
Females
<12 months: not established
1-17 years: 7-20 mg/dL
≥18 years: 6-21 mg/dL
CREATININE
Males
0-11 months: 0.17-0.42 mg/dL
1-5 years: 0.19-0.49 mg/dL
6-10 years: 0.26-0.61 mg/dL
11-14 years: 0.35-0.86 mg/dL
≥15 years: 0.74-1.35 mg/dL
Females
0-11 months: 0.17-0.42 mg/dL
1-5 years: 0.19-0.49 mg/dL
6-10 years: 0.26-0.61 mg/dL
11-15 years: 0.35-0.86 mg/dL
≥16 years: 0.59-1.04 mg/dL
eGFR
>60 mL/min/BSA
Estimated GFR calculated using the 2009 CKD_EPI creatinine equation.
CALCIUM
<1 year: 8.7-11.0 mg/dL
1-17 years: 9.3-10.6 mg/dL
18-59 years: 8.6-10.0 mg/dL
60-90 years: 8.8-10.2 mg/dL
>90 years: 8.2-9.6 mg/dL
GLUCOSE
0-11 months: not established
≥1 year: 70-140 mg/dL
Total Protein
≥1 year: 6.3-7.9 g/dL
Reference values have not been established for patients who are <12 months of age.
ALBUMIN
≥12 months: 3.5-5.0 g/dL
Reference values have not been established for patients who are <12 months of age.
PHOSPHORUS
Males
1-4 years: 4.3-5.4 mg/dL
5-13 years: 3.7-5.4 mg/dL
14-15 years: 3.5-5.3 mg/dL
16-17 years: 3.1-4.7 mg/dL
≥18 years: 2.5-4.5 mg/dL
Reference values have not been established for patients that are less than 12 months of age.
Females
1-7 years: 4.3-5.4 mg/dL
8-13 years: 4.0-5.2 mg/dL
14-15 years: 3.5-4.9 mg/dL
16-17 years: 3.1-4.7 mg/dL
≥18 years: 2.5-4.5 mg/dL
Reference values have not been established for patients that are less than 12 months of age.
Interpretation
Renal function panel results are not diagnostic but rather indicate that there may be a problem with the kidneys and that further testing is required to make a diagnosis and determine the cause. Results of the panel are usually considered together, rather than separately. Individual test result can be abnormal due to causes other than kidney disease, but taken together with risks and signs and symptoms, they may give an indication of whether kidney disease is present.
Clinical Reference
1. Oh MS: Evaluation of renal function, water, electrolytes, and acid-base balance. In Henry's Clinical Diagnosis and Management by Laboratory Methods. 22nd edition. Edited by RA McPherson, MR Pincus. Philadelphia, PA: Elsevier Saunders; 2011:chap 14
2. AACC: Lab Tests Online: Access 03/22/2017. Available at https://labtestsonline.org/understanding/analytes/bmp
Day(s) and Time(s) Performed
Monday through Sunday; Continuously
Analytic Time
Same day/1 dayTest Classification
This test has been cleared, approved or is exempt by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
KS: 84132
NAS: 84295
CL: 82435
HCO3: 82374
BUN: 84520
CRTS1: 82565
CA: 82310
GLURA: 82947
ALB: 82040
PHOS: 84100
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| RFAMA | Renal Function Panel, S | 24362-6 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| AGAP | Anion Gap | 33037-3 |
| ALB | Albumin, S | 1751-7 |
| BUN | Bld Urea Nitrog(BUN), S | 3094-0 |
| CL | Chloride, S | 2075-0 |
| GLURA | Glucose, Random, S | 2345-7 |
| HCO3 | Bicarbonate, S | 1963-8 |
| PHOS | Phosphorus (Inorganic), S | 2777-1 |
| CA | Calcium, Total, S | 17861-6 |
| NAS | Sodium, S | 2951-2 |
| KS | Potassium, S | 2823-3 |
| CRTSA | Creatinine, S | 2160-0 |
| EGNB | eGFR-Non Black | 88294-4 |
| EGBL | eGFR-Black | 88293-6 |
Forms
If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.